Flavin News: Our Research Activity
Reduced Molecular Flavins as Single-Electron Reductants after Photoexcitation
Flavins are not just oxidants - they are excellent reductants as well! Inspired by the activity of DNA photolyase, Richard successfully searched for conditions to replace the rare-earth reductant samarium(II)iodide by flavin catalysis and discovered a mild procedure using gamma-terpinene as stoichiometric reductant.
Photochemical Deracemization at sp3-Hybridized Carbon Centers via a Reversible Hydrogen Atom Transfer
In a collaboration with the Bach Lab, we were interested in the different molecular geometries of assemblies between hydantoin substrates and a chiral photocatalyst. Fascinatingly, the different binding of enantiomeric substrates allows very efficient deracemization via hydrogen atom transfer (HAT).
Molecular Editing of Flavins for Catalysis
In this Short Review, we give an overview of current strategies in tailoring molecular flavins for specific catalytic applications. We put special emphasis on linking the position of modification to changes in catalyst activity.
Synthetic C‐6 Aminoflavin Catalysts Enable Aerobic Bromination of Oxidation‐Prone Substrates
Our first independent group's research paper describes synthetic flavin catalysts, which allow bromination of tyrosine derivatives and other oxidation-prone substrates. We use inorganic halide salt and capitalize on reactivity that is known with flavoenzymes.
Site‐Selective Nitrene Transfer to Conjugated Olefins Directed by Oxazoline Peptide Ligands
A Fast and Reliable Screening Setup for Homogeneous Catalysis with Gaseous Reactants at Extreme Temperatures and Pressures
Intramolecular [2+2] Photocycloaddition of Cyclic Enones: Selectivity Control by Lewis Acids and Mechanistic Implications
Terahertz Spectroscopy of Tetrameric Peptides
Troponoid Atropisomerism: Studies on the Configurational Stability of Tropone-Amide Chiral Axes
A Stereodynamic Redox-Interconversion Network of Vicinal Tertiary and Quaternary Carbon Stereocenters in Hydroquinone-Quinone Hybrid Dihydrobenzofurans
Supramolecular chirality transfer in stereodynamic catalysts
Investigation of Strain-Promoted Azide–Alkyne Cycloadditions in Aqueous Solutions by Capillary Electrophoresis
Attracting Enantiomers: Chiral Analytes That Are Simultaneously Shift Reagents Allow Rapid Screening of Enantiomeric Ratios by NMR Spectroscopy
Stereodynamic Quinone–Hydroquinone Molecules That Enantiomerize at sp3-Carbon via Redox-Interconversion
By-design enantioselective self-amplification based on non-covalent product–catalyst interactions
Temperature-Controlled Bidirectional Enantioselectivity in Asymmetric Hydrogenation Reactions Utilizing Stereodynamic Iridium Complexes
A stereodynamic phosphoramidite ligand derived from 3,3′-functionalized ortho -biphenol and its rhodium(I) complexen A stereodynamic phosphoramidite ligand derived from 3,3′‐functionalized ortho‐biphenol and its rhodium(I) complex
Rotational Barriers of Substituted BIPHEP Ligands: A Comparative Experimental and Theoretical Study
Stereodynamic tetrahydrobiisoindole “NU-BIPHEP(O)”s: functionalization, rotational barriers and non-covalent interactions
Temperature-Controlled Bidirectional Enantioselectivity in a Dynamic Catalyst for Asymmetric Hydrogenation
Tautomerization-Mediated Molecular Switching Between Six- and Seven-Membered Rings Stabilized by Hydrogen Bonding
CuII-selective bispidine–dye conjugates
5,5′-Diamino-BIPHEP ligands bearing small selector units for non-covalent binding of chiral analytes in solution
Skeleton Decoration of NHCs by Amino Groups and its Sequential Booster Effect on the Palladium-Catalyzed Buchwald-Hartwig Amination
Synthesis of Molecular Gallium Hydrides by Means of Low-Temperature Catalytic Dehydrogenation
Straightforward Synthesis of Poly(dimethylsiloxane) Phases with Immobilized (1R)-3-(Perfluoroalkanoyl)camphorate Metal Complexes and Their Application in Enantioselective Complexation Gas Chromatography